Science - May 6 2005.pdf

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6 May 2005
Vol. 308 No. 5723
Pages 741–908
$10
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GE Healthcare
4x greater binding capacity
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Ni Sepharose ™ products from GE Healthcare give you the highest binding
capacity available for histidine-tagged protein purification. With up to four times
the binding capacity, it’s no longer pure imagination to dramatically increase your
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thanks to tolerance of a wide range of additives and negligible nickel ion leakage.
The flexibility to use a variety of protocols ensures the highest possible purity.
Ni Sepharose 6 FF is excellent for manual procedures such as gravity/batch and
easy scale-up, while the HP version is designed for high-performance in automated
purification systems – both are available in different formats, including prepacked
columns. Outstanding performance has never been easier to achieve.
© 2005 General Electric Company - All rights reserved.
Amersham Biosciences AB, a General Electric company
going to market as GE Healthcare.
GE10-05
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S PECIAL I SSUE
D ISTRIBUTED C OMPUTING
Computers processing data for the Oxford University project ClimatePrediction.net
(see page 810 ). Scientific computing ventures in fields as varied as number theory,
genomics, and particle physics have asked people to donate their computers’ spare
CPU cycles to create a virtual machine that dwarfs the top supercomputers. [Image:
Chris Valentine/hockeyphotos.com; Martin Dzbor/KMi, Open University]
Volume 308
6 May 2005
Number 5723
I NTRODUCTION
809
T. Hey and A. E. Trefethen
Biomedical Research
K. H. Buetow
Related Editorial page 757 ; News story page 773
N EWS
810
Grid Sport: Competitive Crunching
813
V IEWPOINTS
814
For related online content in STKE,
see page 751 or go to
D EPARTMENTS
N EWS F OCUS
751
778
The Dark Side of Glia
753
757
David A. Patterson
An Endless Frontier Postponed
related Distributed Computing section page 809
782
Embryologists Polarized Over Early Cell Fate
Determination
785
Electronic Paper: A Revolution About to Unfold?
Shrinking Dimensions Spur Research Into Ever-Slimmer
Batteries
759
764
769
877
787
Changes in the Sun May Sway the Tropical
Monsoon
related Report page 854
884
N EWS OF THE W EEK
770
A Heavyweight Battle Over CDC’s
Obesity Forecasts
788
L ETTERS
791
771
Picture-Perfect Planet on Course for the
History Books
Establishing Indicators for Biodiversity J. Brauer;
B. Czech et al . Response A. P. Dobson et al . Memo to
NASA: Finish What You Start C. J. Robinove. The End
of a Chilean Institute L. Barbeito et al .
B OOKS ET AL .
778
773
IBM Offers Free Number Crunching for
Humanitarian Research Projects related
Distributed Computing section page 809
794
The Goddess and the Bull Çatalhöyük: An
Archaeological Journey to the Dawn of Civilization
M. Balter, reviewed by S. Mithen
773
774
Chemists Want NIH to
Curtail Database
795
774
Panel Gives Thumbs-Down to
European Institute of
Technology
796
Pleistocene Park: Return of the
Mammoth’s Ecosystem
S. A. Zimov
P ERSPECTIVES
775
Celera to End Subscriptions and Give Data
to Public GenBank
796
777
U.S. Lawmakers Call for New Earth Science
Strategy
799
Attractors in Memory
B. Poucet and E. Save
related Report page 873
777
Two-Thirds of Senate Backs More Research
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745
SCIENCE
VOL 308
6 MAY 2005
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