Cytoskeleton4.pdf

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Cytoskeleton
Made of proteins
Dynamic properties
Coordinate with each other
Coordinate with external signal
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Biological functions of the cytoskeleton
Tissue level
Cell level
Muscle movement
Cell shape
Cell movement
Cell adhesion
Mitosis
Subcellular level
Intracellular movement of vesicles
Location of subcellular organelles
Organizing cell polarity
Endocytosis – clathrin-mediated endocytosis and
phagocytosis
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Actin cytoskeleton
-
+
G-actin
F-actin
Mg ++
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Microtubule
Taxol
Non exchangeable
Exchangeable
+
-
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Polymerization of G-actin
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